http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104922126-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-431 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2015-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104922126-B |
titleOfInvention | A kind of piperacillin sodium and tazobactam sodium sterile powder injection and preparation method thereof |
abstract | The invention provides a kind of piperacillin sodium and tazobactam sodium sterile powder injection, component includes:68 parts of avocin, 1 part of sodium-tazobactam, 40 80 parts of mannitol, 10 30 parts of vitamin C, 8 15 parts of sodium pyrosulfite, 5 10 parts of glycine.Under inert gas shielding, each component is dissolved with water for injection;Activated carbon decolorizing is added, is then filtered to remove activated carbon;With 0.22 μm of 0.80 μm of miillpore filter refined filtration;Freeze-drying, is produced.Compared with prior art, the stabilizer that the present invention is formed using mannitol, vitamin C, sodium pyrosulfite and glycine, it is effectively improved the stability of preparation, preparing and the stabilization in storing process, avocin and sodium-tazobactam it is substantially unchanged, polymer content is low, ensures that product is qualified in the term of validity, the effect of ensure that Clinical practice and security.Preparation method is simple, and cost is low, is suitable for industrialized production. |
priorityDate | 2015-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.