http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104922069-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-37
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filingDate 2015-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104922069-B
titleOfInvention A kind of nano gold spherical shell photosensitive liposomes and preparation method thereof
abstract A kind of nano gold spherical shell photosensitive liposomes, the drug-loading system is by conventional medicine liposome and gold nano-spherical shell structure composition.The preparation method of the photosensitive liposomes is mainly: first in the surface of liposome combination cysteine for being coated with wedelolactone, making its surface rich in mercapto groups;Then reducing agent sodium borohydride reduction chlorauride is utilized, gold nano grain is obtained;Mercapto-modified liposome is mixed in a certain ratio with gold nano grain finally, and is incubated under given conditions to get nano gold spherical shell photosensitive liposomes are arrived.The present invention can normal temperature and pressure and it is mild under conditions of complete, simple process reacts easily controllable, obtained liposome morphological rules, and particle diameter distribution can effectively absorb 700-850nm near infrared light in 200-250nm, and have splendid photothermal conversion performance.
priorityDate 2015-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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