| abstract |
The invention disclosed herein relates to compounds of formula I useful in the treatment of prostate cancer, breast cancer, colon cancer, pancreatic cancer, human chronic lymphocytic leukemia, melanoma and other cancers: and pharmaceutically acceptable salts thereof. The present invention also includes pharmaceutical compositions comprising a therapeutically effective amount of a compound of formula I or a pharmaceutically acceptable salt thereof. The invention disclosed herein also relates to methods of treating prostate cancer, breast cancer, ovarian cancer, liver cancer, kidney cancer, colon cancer, pancreatic cancer, human chronic lymphocytic leukemia, melanoma, and other cancers. The invention disclosed herein additionally relates to methods of treating prostate cancer, breast cancer, colon cancer, pancreatic cancer, chronic lymphocytic leukemia, melanoma, and other cancers comprising administering a therapeutically effective amount of a selective PPARĪ± antagonist. The compounds and pharmaceutical compositions of the invention are also useful in the treatment of viral infections, such as HCV infection and HIV infection. |