http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104910265-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-463 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate | 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104910265-B |
titleOfInvention | A kind of gene and the application of Hejiang spine frog antibacterial peptide and its coded sequence |
abstract | The invention discloses a kind of Hejiang spine frog cathelicidin antibacterial peptide cathelicidin PR1, and it is with SEQ ID NO in sequence table:Nucleotide sequence coded albumen shown in 1, or by SEQ ID NO:2 amino acid residue sequence passes through substitution, missing or the addition of more than one amino acid residue, and has and SEQ ID NO:2 amino acid residue sequence is identical active by SEQ ID NO:Protein derived from 2.Present invention clone obtains Hejiang spine frog antibacterial peptide cathelicidin PR1 encoding gene, and has synthesized cathelicidin PR1 using the method for chemical synthesis.The antibacterial peptide molecular weight is small, and in the amphipathic structure of α spirals, bactericidal action is fast, to Pseudomonas Maltophilia 7404, staphylococcus aureus(Song), Bacillus cereus, bacillus subtilis, Candida albicans 08030102 and Candida glabrata 08A802 there is strong killing action.In addition, also there is extremely low hemolytic activity and antioxidation activity, without hemagglutination activity. |
priorityDate | 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.