http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104910212-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0093 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 |
| filingDate | 2015-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104910212-B |
| titleOfInvention | A kind of schiff bases platinum complex and its preparation method and application |
| abstract | The invention provides the application of a kind of schiff bases platinum (II) complex and preparation method thereof, and the complex.Schiff bases platinum (II) coordination chemistry formula of the present invention is：Pt [X PMP] [DMSO] Cl, wherein X PMP=4 X 2 [(phenyl imine) methyl] phenol (X=Cl or NO 2 ).Its preparation method：Weigh reactants of X PMP to be dissolved in methanol solution, the triethylamine that mole is 1~2 times of the reactant is added dropwise thereto, under stirring, by the Pt (DMSO) with X PMP equimolar amounts 2 Cl 2 It is added in above-mentioned reaction solution, reaction solution lucifuge and logical nitrogen protection, heating reflux reaction 1~4 hour separate out solid product.Complex preparation method of the present invention is simple, and raw material is easy to get, and cost is relatively low.Biological activity test detection shows that the complex can not only effectively suppress can be active as the PTP1B of antineoplastic target spot, and has significant inhibitory action to Cells Proliferation of Human Breast Cancer, can be applied in antineoplastic is prepared. |
| priorityDate | 2015-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.