http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104910172-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104910172-B |
| titleOfInvention | Five kinds of talan trimer preparation methods and its application |
| abstract | Five kinds of talan trimer preparation methods and its application, using external α glucosidase inhibitory actives to be oriented to, that instructs the Chinese medicine rhizome of nutgrass flatsedge isolates and purifies process, and the preparation method includes：Medicinal material ultrasonic extraction, silica gel column chromatography separation, macroporous resin column chromatography separation, gel filtration chromatography separation, anti-phase preparation HPLC separation.Identified through HR MS and NMR, five kinds of talan tripolymers are：(±)‑(E)‑cyperusphenol A、(E)‑mesocyperusphenol A、cyperusphenol C、cyperusphenol B、cyperusphenol D.In addition, present invention firstly discloses inhibitory action of five kinds of talan tripolymer compounds to α glucuroides, and it is used as the application for preparing α glucosidase inhibitor medicines.Proved through pharmacological evaluation, five kinds of talan tripolymer compounds are respectively provided with very strong external α glucosidase inhibitory actives, its activity is compared with positive control drug（Acarbose）It is strong 1000 times, more known talan dimer（Scirpusin A and scirpusin B）It is strong 5 10 times. |
| priorityDate | 2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.