http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104910155-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66af08c4541f710a579f4c8fda921420 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2015-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae243c12ccc56f5a56d8725b6dd88b8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e65ef6d343f20fc341c09c8d33886d73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_569cc749d88e9e0ed0a37c9f09a156f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b3d6748d19ed6f8bcf8c8121cfb715d |
| publicationDate | 2015-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104910155-A |
| titleOfInvention | 3-Iodo-6-chloro-imidazo [1,2-a] pyridine synthetic method |
| abstract | The present invention belongs to the field of organic synthesis, and in particular relates to a 3-iodo-6-chloro-imidazo [1,2-a] pyridine synthetic method. The synthetic method comprises the following steps: 2-amino-5-chloropyridine, A chloroacetaldehyde aqueous solution, and N-iodosuccinimide are used as raw materials for continuous reaction under the action of a base in a suitable solvent at 40-150 DEG C to obtain a 3-iodo-6-chloro-imidazo [1,2-a] pyridine crude product, wherein the ratio of the number of moles of 2-amino-5-chloropyridine to chloroacetaldehyde aqueous solution is 1: 0.7-2.8, the ratio of the number of moles of 2-amino-5-chloropyridine to N-iodosuccinimide is 1: 1.0-3.1, and the 3-iodo-6-chloro-imidazo [1,2-a] pyridine crude product is purified to obtain a 3-iodo-6-chloro-imidazo [ 1,2-a] pyridine pure product. Reaction raw materials are relatively easy to obtain, and are reasonable in prices, the reaction are mild in conditions, easy to operate, and easy to control, post-processing is simple, product quality is stable, and purity is high. |
| priorityDate | 2015-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.