http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104910126-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d708a07486c27db90c59dff5b44f364 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-36 |
| filingDate | 2015-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17d81c4307deb4f94ad631c07f86a5ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ece44aa50e11bc6e90184339ce68a3fd |
| publicationDate | 2015-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104910126-A |
| titleOfInvention | Extracting and separating method and application for Machilin A |
| abstract | The invention relates to an extracting and separating method and application for Machilin A. The extracting and separating method comprises the following steps: (1) crushing dry barks of Machilus thunbergii, adding an ethanol aqueous solution, carrying out negative pressure-cavitation suspension solid-liquid extraction so as to obtain an extract, recovering a reagent from the extract so as to obtain a total alkaloid extract; (2) adding macroporous resin into the total alkaloids extract, carrying out uniform mixing and drying, then carrying out packing, carrying out eluting with an alcohol-water solution, collecting Machilin A fraction, and carrying out condensation so as to obtain crude Machilin A; and (3) subjecting the above-mentioned crude Machilin A to separation and purification by using a high-speed countercurrent chromatography method so as to obtain the Machilin A. The method in the invention has the advantages of high product content, simple operation, high efficiency, etc. The compound prepared by using the method in the invention opens up a novel path for the development and application of a new generation of antitumor drugs with natural resources. |
| priorityDate | 2015-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.