http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104910114-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d708a07486c27db90c59dff5b44f364 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-92 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 |
| filingDate | 2015-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ece44aa50e11bc6e90184339ce68a3fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17d81c4307deb4f94ad631c07f86a5ca |
| publicationDate | 2015-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104910114-A |
| titleOfInvention | Preparation method of Ivalin and application of Ivalin in anti-leukemia drugs |
| abstract | The invention discloses a preparation method and application of a plant extract, and particularly relates to a preparation method of Ivalin and the application of the Ivalin in anti-leukemia drugs. The preparation method comprises the following steps: crushing microcephalic Ivalin or whole herb of an inula flower; adding biological enzymes for enzymolysis for 8-10 hours; adding an ethanol solution of 60-80% to enzymolysis raw materials for microwave extraction or ultrasonic extraction for 2-3 times; concentrating an extracting solution so as to obtain extractum; adding an appropriate amount of water, and after dispersal, adding the dispersed extractum to a macroporous resin column for adsorption; and performing steps of preparative high-efficiency liquid chromatography separation and the like so as to obtain the Ivalin. When the preparation method disclosed by the invention is adopted, the technological operation is simple and convenient, the yield is high, the pollution is low, and the preparation method is suitable for the production of high-purity Ivalin. The Ivalin has the effect of antitumor, pharmacological experiments indicate that the Ivalin has a good effect in the respect of antitumor and particularly has a good effect on human lymphocytic leukemia (P388), so that the Ivalin can be used for preparing the anti-leukemia drugs. |
| priorityDate | 2015-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.