http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104892472-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-65 |
| filingDate | 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104892472-B |
| titleOfInvention | Double chiral sulfoxides-alkene part compounds and its preparation method and application |
| abstract | The present invention relates to double chiral sulfoxide alkene part compounds and its preparation method and application, in organic solvent, controlling reaction temperature is 15 DEG C～40 DEG C, with near amino thiophenols sodium and allyl carbonate methyl compound as raw material, with [Ir (COD) Cl] 2 With part effect generate iridium complex as catalyst, under the effect of additive, react 12 24h prepare 3 substituted allyl neighbour's aminobenzene thio-ether type compounds.3 substituted allyl neighbour's aminobenzene thioethers obtain 3 substituted propyl neighbour's aminobenzene thio-ether type compounds through reduction.Aoxidized by m-chloro-benzoic acid peroxide subsequently, obtain adjacent amino sulfoxide compound.Finally with 3 replacement α, β unsaturated aldehyde is condensed, and through sodium borohydride reduction, obtains double chiral sulfoxide alkenes part.The method step is succinct, and chiral source and ligand structure skeleton are all independent original.Meanwhile, can apply in the asymmetric allylation of metal rhodium catalysis, and obtain good result. |
| priorityDate | 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 123.