http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104892461-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06 |
filingDate | 2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104892461-B |
titleOfInvention | Lacosamide analogue and preparation method thereof |
abstract | The invention discloses a Lacosamide analogue and a preparation method thereof, and provides the Lacosamide analogue shown in a formula (I). The invention further provides the preparation method of the Lacosamide analogue shown in the formula (I), including: subjecting a compound shown in a formula (II) and methylated solution in two-phase solvent of organic solvent and water, and in the presence of alkali and phase transfer catalyst to substitution reaction for 20 to 100 hours, so as to obtain the compound shown in the formula (I). The Lacosamide analogue shown in the formula (I) is a necessity for quality control of Lacosamide; the preparation method can be used for efficiently synthesizing the analogue. |
priorityDate | 2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.