abstract |
The invention discloses a synthesis method for preparing 1,2-diketone derivatives through alkyne compounds. The method is as follows: under a nitrogen atmosphere, zinc salt is used as a catalyst, an alkyne compound, an oxidizing agent and an organic solvent are mixed, and the 1,2-diketone derivative is obtained by heating and reacting. The invention has broad substrate compatibility, mild conditions and high synthesis yield. The catalyst used in the invention is a cheap and environment-friendly metal zinc salt, and the substrate used is a simple and easy-to-obtain alkyne compound, which has the advantages of low cost, high yield, simple operation, readily available raw materials, and easy industrial production. |