http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104876853-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22 |
| filingDate | 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104876853-B |
| titleOfInvention | The synthetic method of fexofenadine hydrochloride |
| abstract | The invention discloses the synthetic method of fexofenadine hydrochloride; the synthetic method of fexofenadine hydrochloride of the invention is raw material with 2 (4 bromophenyl) 2 methylpropanoic acids (2); by itself and nafoxidine reaction protection carboxyl, then reacted with gamma butyrolactone, generate compound 6; compound 6 reacts with paratoluensulfonyl chloride; product again with α, the piperidine carbinols of α diphenyl 4 condensation, by reduction; deprotection, is finally obtained target compound 1.This route is raw materials used cheap and easy to get, and reaction condition is gentle, and simple to operation, environmental pollution is smaller, is an industrialized route with preferable application prospect. |
| priorityDate | 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.