http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104876851-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac31afbea1cbbb03498644721ffb4a62 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
filingDate | 2015-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aff9ecce90ad72fa12b16e4397bb5a28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8430571dd65611a3115674708737fd97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c9d0ed500fe1d1c3e2dcaf42e91980b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6b4f1156ce6a0404380eb3816cc8ccc |
publicationDate | 2015-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104876851-A |
titleOfInvention | Preparation method of a class of piperazine derivatives containing indole-3 carboxylic acid skeleton and application in anticancer drugs |
abstract | The invention discloses a class of piperazine derivatives containing an indole-3 carboxylic acid skeleton, related preparation methods and applications in the preparation of antitumor drugs. The preparation method has the following general formula: The invention has obvious inhibitory effect on cervical cancer cells (HeLa). Therefore, the piperazine derivatives containing indole-3 carboxylic acid skeleton disclosed by the present invention have better biological activity, higher selectivity and lower toxicity. |
priorityDate | 2015-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.