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Outgoing Links

Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-536
filingDate 2015-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104873570-B
titleOfInvention A kind of method for extraction and purification of Prunella vulgaris general flavone and its application
abstract A kind of method for extraction and purification of Prunella vulgaris general flavone, step are as follows: (1) take Prunella vulgaris pulverizing medicinal materials to be sieved, add the 1-30 times of ethyl alcohol for measuring 5-95%, refluxing extraction 1-3 times, each 1-5 h is filtered, and merging filtrate obtains extracting solution;(2) extracting solution heating is concentrated into concentration is 0.05-0.5 g/mL, then adjusting pH value is 1-7, obtains sample solution;(3) by the sample solution, upper NKA-9 macroporous absorbent resin, after the removal of impurities of 1-10 BV water, then with the 10-95% ethanol elution of 1-10BV;(4) purifying process of the continuous several times Jing Guo step 3 obtains enriched substance, be dried under reduced pressure to powder or medicinal extract to get.The present invention also provides application of the Prunella vulgaris general flavone in preparation treatment liver-cancer medicine, by pharmacological effect research shows that Prunella vulgaris general flavone has apparent anti-liver tumour activity, and be in apparent dose-effect relationship, theoretical and experimental basis is provided by the anti-liver tumour new drug and industrial production of raw material being worth with extensive clinical use value and business development of Prunella vulgaris general flavone enriched substance to develop.
priorityDate 2015-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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