http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104873570-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-536 |
filingDate | 2015-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104873570-B |
titleOfInvention | A kind of method for extraction and purification of Prunella vulgaris general flavone and its application |
abstract | A kind of method for extraction and purification of Prunella vulgaris general flavone, step are as follows: (1) take Prunella vulgaris pulverizing medicinal materials to be sieved, add the 1-30 times of ethyl alcohol for measuring 5-95%, refluxing extraction 1-3 times, each 1-5 h is filtered, and merging filtrate obtains extracting solution;(2) extracting solution heating is concentrated into concentration is 0.05-0.5 g/mL, then adjusting pH value is 1-7, obtains sample solution;(3) by the sample solution, upper NKA-9 macroporous absorbent resin, after the removal of impurities of 1-10 BV water, then with the 10-95% ethanol elution of 1-10BV;(4) purifying process of the continuous several times Jing Guo step 3 obtains enriched substance, be dried under reduced pressure to powder or medicinal extract to get.The present invention also provides application of the Prunella vulgaris general flavone in preparation treatment liver-cancer medicine, by pharmacological effect research shows that Prunella vulgaris general flavone has apparent anti-liver tumour activity, and be in apparent dose-effect relationship, theoretical and experimental basis is provided by the anti-liver tumour new drug and industrial production of raw material being worth with extensive clinical use value and business development of Prunella vulgaris general flavone enriched substance to develop. |
priorityDate | 2015-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.