http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104873499-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4155 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4155 |
filingDate | 2015-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104873499-B |
titleOfInvention | A kind of application of compound of up-regulation Runx2 transcriptional activities in osteoporosis is prevented and treated |
abstract | The invention belongs to field of medicaments, cell model is adjusted on Runx2 transcriptional activities by building, screening obtains compound N (Cvclopropvlmethvl) 5 (base of thiophene 2) 1, the formamide of 2 azoles 3, experimental study shows that it has the expression of up-regulation Runx2 transcriptional activity, up-regulation Gegenbaur's cell alkaline phosphatase activity and skeletonization specific differentiation gene, increase the generation of calcium scoring simultaneously, with the application prospect for preparing preventing and treating medicine for treating osteoporosis. |
priorityDate | 2015-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 271.