http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104870445-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate | 2013-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104870445-B |
titleOfInvention | New dihydro-pyrimidin and isobioquin group and its pharmaceutical composition (GPR84 antagonists) for treating inflammatory disease |
abstract | According to formula (Ia) compound, wherein Cy, L 1 , G and R 1 It is as described herein. The present invention relates to antagonism involve in inflammatory disease g protein coupled receptor GPR84 according to formula (I) noval chemical compound, the method for preparing these noval chemical compounds, the pharmaceutical composition comprising these compounds, and pass through and apply the compound of the present invention and be used for the method preventing and/or treat following disease:Inflammatory disease (such as inflammatory bowel disease (IBD), rheumatoid arthritis, vasculitis), tuberculosis (such as chronic obstructive pulmonary disease (cOPD) and interstitial diseases (such as idiopathic pulmonary fibrosis (IPF))), neuroinflammatory disorder, infectious diseases, autoimmune disease, endocrine and/or metabolic disease and/or it is related to the impaired disease of immune cell function. |
priorityDate | 2012-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 843.