http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104861075-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
filingDate | 2015-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104861075-B |
titleOfInvention | A kind of long-acting recombinant human brain natriuretic peptide fusion protein and preparation method thereof and purposes |
abstract | The invention discloses a kind of long-acting recombinant human brain natriuretic peptide fusion protein (Human Brain Natriumretic Fc fusion protein, abbreviation hBNP Fc) and preparation method thereof, its single-stranded amino acid sequence of the fusion protein includes people BNP (hBNP), peptide linker and human IgG 4Fc variants successively from N-terminal to C-terminal.The fusion protein has similar with rhBNP or higher biological activity, longer half-life period, smaller side effect.The invention further relates to purposes of the recombination hBNP Fc fusion protein compositions in the drug for preparing treatment and/or prevention acute heart failure. |
priorityDate | 2015-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 326.