| abstract |
The invention discloses an imidazopyrimidinone compound represented by formula (I), a preparation method and application thereof. Wherein, n, R and Ar are as described in the specification, the compound of the present invention and its pharmaceutically acceptable salt can stimulate the production of human tumor necrosis factor-related apoptosis-inducing ligand, and can avoid existing recombinant protein and antibody-based The malpractice of the treatment method provides a new option for the treatment of related tumors. |