http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104844648-B

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Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-177
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-18
filingDate 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104844648-B
titleOfInvention A kind of synthetic method of group thiophosphate compound
abstract The present invention relates to a kind of synthetic method of group thiophosphate compound.The present invention, in the dichloro 5 of chlorination reagent 1,3, thiophosphate is synthesized under the promotion of 5 DMHs/sym-closene using phosphite ester and thiophenol or mercaptan.Mild condition, is swift in response, and course of reaction need not add alkali and catalyst, have wide applicability to the substrate of different functional groups.The phosphorothioate backbone that the present invention is efficiently built is the important skeleton of many medicines, agricultural chemicals, bioactive molecule and natural products, and synthetic method of the present invention provides a generally applicable preparation method for the synthesis of this kind of compound.
priorityDate 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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