http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104840973-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 |
| filingDate | 2015-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104840973-B |
| titleOfInvention | Escitalopram transdermal skin patches and preparation method thereof |
| abstract | The invention belongs to pharmaceutical technology field, is related to escitalopram transdermal skin patches and preparation method thereof.The escitalopram transdermal skin patches are carried medicine pressure-sensitive adhesive layer and adherent layer are formed by back sheet；Carrying medicine pressure-sensitive adhesive layer includes escitalopram free alkali or its organic acid ion to compound, pressure sensitive adhesive, transdermal absorption accelerator.Wherein escitalopram free alkali or its organic acid ion account for the total dose of compound 2.0 20wt% for carrying medicine pressure-sensitive adhesive layer gross weight, and pressure sensitive adhesive accounts for 77 97wt% of gross weight, and transdermal absorption accelerator dosage accounts for 0 6.8wt% of gross weight.The escitalopram organic acid ion is in compound, the ratio of escitalopram free alkali and different organic acids is 0.5:1‑2:1.Escitalopram organic acid ion provided by the invention is to compound percutaneous absorption patch compared with escitalopram free alkali percutaneous absorption patch, it is possible to provide up to the insoluble drug release of the approximately constant speed of 7 days, patient medication compliance is greatly improved. |
| priorityDate | 2015-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.