| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 |
| filingDate |
2013-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-104837837-B |
| titleOfInvention |
As the thiazole of bruton's tyrosine kinase inhibitor |
| abstract |
This application discloses the compound of the logical formula (I) of Btk can be suppressed, wherein all variables are as defined herein.Compounds as disclosed herein can be used for the activity for adjusting Btk and can be used to treat the disease relevant with excessive Btk activity.The compound can be additionally used in treating the inflammatory relevant with exception B cell propagation and autoimmune disease such as rheumatoid arthritiss.The invention also discloses the compositionss containing compound of formula I and at least one carrier, diluent or excipient. |
| priorityDate |
2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |