http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104830930-B

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classificationIPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-225
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-40
filingDate 2015-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104830930-B
titleOfInvention A kind of production method of 2 '-deoxyguanosine of nucleoside medicine intermediate
abstract The invention belongs to biotechnologies, it is related to the technical field that biological catalysis prepares 2 ' deoxyguanosines, specially a kind of production method of 2 ' deoxyguanosine of nucleoside medicine intermediate, this method, using β thymidines and guanine as raw material, it uses lactobacillus fermenti thalline slurry for biocatalyst, biocatalytic reaction is carried out under polyethylene glycol 10000/dipotassium hydrogen phosphate aqueous two-phase system, obtain 2 ' deoxyguanosine products.Under optimal condition, substrate β thymidine additions reach 16.5g/L, and for thymidine conversion ratio up to 89%, 2 ' deoxyguanosine of product reaches 16.1g/L.
priorityDate 2015-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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