abstract |
The present invention relates to medicinal chemistry arts, the new method that more particularly to a kind of nucleoside phosphoramidate class mother liquid medicine is recycled.The present invention be directed to current synthetic route in industrialized production, industrialization yield is relatively low, the relatively costly problem of production, there is provided the new method that a kind of nucleoside phosphoramidate class mother liquid medicine is recycled.After this kind of nucleoside phosphoramidate class mother liquid medicine is through a series for the treatment of, recyclable chemical compounds I and compounds Ⅳ, process is simple are adapted to industrial mass production. |