http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104829635-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F1-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
filingDate | 2015-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104829635-B |
titleOfInvention | Metal copper complexes of serine N derivant and its preparation method and application |
abstract | The invention provides the metal copper complexes of serine N derivant, its molecular formula is respectively as follows: [CuL1Cl (H 2 O)](1)、[Cu(L2) 2 ]·H 2 O (2), wherein HL1 is N (2 picolyl) L serine;HL2 is N (4 hydroxy phenyl) L serine.The preparation method of coordination compound is in the part aqueous solution that the aqueous solution of mantoquita is added drop-wise to be placed in round-bottomed flask, is stirred at room temperature 5~9h, filters, and filtrate is slowly volatilized and separated out blue bulk crystals, and productivity is more than 50%.Both coordination compounds have efficient inhibitory action to the activity of Protein-tyrosine-phosphatase (PTPs), and coordination compound 2 demonstrates preferable selectivity to PTP1B. |
priorityDate | 2015-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.