abstract |
The present invention provides an inhibitor of Bruton's tyrosine kinase, which is a compound of formula (I), or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides pharmaceutical compositions comprising said compounds. The present invention also provides methods and methods of using the Bruton's tyrosine kinase inhibitors to inhibit tyrosine kinase activity or to treat diseases, disorders or conditions that benefit from inhibition of Bruton's tyrosine kinase (Btk) activity. use. |