http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104829609-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
filingDate | 2014-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104829609-B |
titleOfInvention | Substituted Pyridopyrimidine compound and its preparation method and application |
abstract | The invention discloses a kind of substituted Pyridopyrimidine compound and its preparation method and application.Shown in formula I, wherein Ar is substituted pyridine radicals to the general structure of shown substituted Pyridopyrimidine compound.The research of the present invention finds that this compounds is a kind of multi-kinase inhibitor, can suppress multiple simultaneously and be present in intracellular and cell surface kinases, including PI3 K and/or mTOR kinases.Thus, this compounds and pharmaceutically acceptable salt thereof can be used for preparing the medicine treating and/or preventing the disease (cancer) that PI3 K and/or mTOR kinases cause. |
priorityDate | 2014-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 177.