abstract |
The invention relates to a synthesis method of glycine derivatives, specifically: in an organic solvent, using glycine ester compounds and indole as raw materials, adding dye EosinY as a catalyst, and adding a Lewis acid additive, at room temperature and 1atm O2 Next, react for 40h, separated and purified. Compared with the prior art, the present invention overcomes the problems of low reaction yield, high temperature requirement, expensive catalyst and heavy metal pollution in other methods, and has the characteristics of high reaction yield, easy operation, and environmental protection. It has a wide range of applications in science and natural product synthesis. |