http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104826123-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
filingDate | 2015-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104826123-B |
titleOfInvention | A kind of inclusion compound of oleanolic acid and amine cyclodextrin |
abstract | The invention discloses a kind of pentacyclic triterpenoid oleanolic acid and the inclusion compound of amine cyclodextrin, described amine cyclodextrin is the beta cyclodextrin of amino substitution, and the inclusion compound is prepared using solvent method or ultrasonic method;After oleanolic acid forms inclusion compound with amine cyclodextrin, its solubility in water greatly improves, stability increase, it is expected to improve its bioavilability.Meanwhile anticancer experiment in vitro shows, the inclusion compound has good anti tumor activity in vitro to several tumor cell lines;Its preparation method is easy, easily operated and reaction condition is gentle, the exploitation available for oleanolic acid novel formulation. |
priorityDate | 2015-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.