abstract |
The present invention proposes a kit of first and second formulations intended to be mixed to form an endodontic irrigant solution prior to or during endodontic treatment. The first formulation comprises an oxidizing agent. The second formulation includes antimicrobial nanoparticles treated to slow oxidation thereof by the oxidizing agent. The antimicrobial nanoparticles are encapsulated within the shell, for example, in a hybrid core-shell structure. In one variation, the antimicrobial nanoparticles are made of an alloy of at least two elements, where one element is more resistant to oxidation than the other element. |