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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
filingDate 2014-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104818320-B
titleOfInvention Primer, probe, detection architecture and the kit of disposable detection lung cancer multiple gene
abstract The invention discloses a kind of primer, probe, detection architecture and kit for detecting lung cancer multiple gene, including for detecting the 25 kinds of mutation of lung cancer EGFR gene, the 7 kinds of mutation of KRAS genes and 5 kinds of 6 kinds of gene mutations of BRAF, 9 kinds of gene mutations of NRAS, HER2 gene mutations, the primer, probe and its method for salary distribution of 5 kinds of fusions of 2 kinds of gene mutations of PIK3CA and ALK, 13 kinds of fusions of ROS1 and 6 kinds of fusions of RET.The detection kit of the present invention detects the multiple gene of a sample using 12 PCR reaction bar designs, each 12 PCR bar, and 1 No. 4 pipes of 12 bracings are built with corresponding fusion detection reagent and internal control reagent.The present invention can realize the 24 kinds of fusions and 54 kinds of mutation of disposable detection lung cancer, substantially reduce the time of detection, and high sensitivity, high specificity is simple and efficient to handle, tumor-targeting drug treatment can be selected to provide reference patients with lung cancer for clinician.
priorityDate 2014-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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