abstract |
The present invention relates to chiral A new method for the synthesis of base derivatives. The present invention designs and synthesizes a chiral ionic liquid 1-pyridine-3,4,6-tri-acetylglucopyranose tetrafluoroborate with glucose as a chiral source, and uses it as a catalyst and solvent for the first direct one-step catalytic synthesis series Chirality base derivative. The invention uses the novel sugar-containing chiral ionic liquid 1-pyridine-3,4,6-tri-acetylglucopyranose tetrafluoroborate as the catalyst, the method is green, environmentally friendly, simple and economical, and can obtain high yield and high yield in one step. of optical purity base derivative. |