http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104803934-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2015-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104803934-B |
| titleOfInvention | A kind of phenyl-isoxazole triazole carboxylic acid's class compound and its synthetic method and application with antitumor activity |
| abstract | The invention discloses general structure（I）Shown compound, wherein, R 1 、R 2 Independently selected from hydrogen, nitro, C1 C4 alkoxy, halogen, substituted or unsubstituted phenyl, substituted or unsubstituted low alkyl group or cycloalkyl, lower alkylcycloalkyl, cycloalkyl low-grade alkyl.Such compound synthesizes to obtain using phenyl isocyanate, ethyl benzoylacetate or its analog, hydroxylamine hydrochloride as raw material using toluene as solvent, and this method processing safety is high, and reaction condition is gentle, suitable for industrialized production.Show that the type compound has preferable antitumor activity through preliminary biological activity test, there are important medical applications to be worth. （I）. |
| priorityDate | 2015-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.