http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104788554-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-555 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-20 |
| filingDate | 2015-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104788554-B |
| titleOfInvention | Cat omega interferon mutant and its preparation method and application |
| abstract | The invention discloses a kind of cat omega interferon mutant and its preparation method and application, belong to the preparation and application field of cat omega interferon.The present invention obtains cat ω 2 or 11 interferon mutant of ω to 2 interferon of cat ω or 11 interferon of ω progress Amino Acid-Induced Site-Directed Mutation by comparing the gene order and amino acid sequence of 13 hypotypes of cat omega interferon.The present invention further discloses the methods for preparing the cat omega interferon mutant, it include: that cat ω gene carries out point mutation, and mutated gene is optimized, the gene cloning of cat ω 2 or 11 interferon mutant of ω will be encoded into baculovirus transfer vector, infected insect host is recombinated with baculoviral, expression alien gene obtains cat omega interferon protein expressioning product.The present invention can make the antiviral activity of 2 interferon of cat ω improve 45% or more by mutation, and optimizing and being mutated to gene can make the antiviral activity of 2 interferon of cat ω improve 96% or more.The method of the present invention simple process, can efficiently, steadily obtain the cat omega interferon that can be used safely, and antiviral activity is in be obviously improved. |
| priorityDate | 2015-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.