http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104788471-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24 |
filingDate | 2015-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104788471-B |
titleOfInvention | A kind of synthetic method of Cefditoren pivoxil Cephalosporins parent nucleus |
abstract | The invention discloses a kind of synthetic method of Cefditoren pivoxil Cephalosporins parent nucleus, the synthetic method is by the carboxylic acid of 7 amino, 3 vinyl, 3 cephem 4 shown in quantitative formula (I), the halo thiazole of 4 methyl 5 shown in formula (II), ionic liquid shown in formula (III), inorganic base or organic base, palladium and triphenylphosphine are added in reactor, terminate within 1~10 hour in reaction at 10~150 DEG C, the post-treated Cefditoren pivoxil Cephalosporins parent nucleus obtained shown in formula (IV) again, in formula (III), R is the alkyl of carbon number 1~10, L ‑ It is BF 4 ‑ Or BF 6 ‑ , |
priorityDate | 2015-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.