http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104788326-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 |
filingDate | 2015-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104788326-B |
titleOfInvention | A kind of synthetic method of ambroxol hydrochloride |
abstract | The invention belongs to pharmaceutical synthesis field, specifically disclose the synthetic method of a kind of ambroxol hydrochloride.The present invention, mainly with 1-Formyl-2-nitrobenzene as initiation material, obtains 2 nitro 3,5 dibromo benzaldehydes after bromination, and gained 2 nitro 3,5 dibromo benzaldehyde reacts with trans 4 aminocyclohexanols again, then becomes salt finally to prepare ambroxol hydrochloride through reduction, hydrochlorate.Synthetic method cost of material of the present invention is low, simple to operate, safety and environmental protection, simplify production process, and improves product yield and product purity, is suitable for industrialized production. |
priorityDate | 2015-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.