http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104788291-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-40 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C35-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-86 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2015-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104788291-B |
titleOfInvention | The antitumor drug and method for application of the detached diterpene-kind compound of Flos Rhododendri Mollis |
abstract | The invention discloses detached diterpene-kind compound in a kind of Flos Rhododendri Mollis, the diterpene-kind compound is kalmanol type diterpene compounds, is 5 hydroxyls of rhodomollein XXIV and 1 hydrogen dehydration product in chemical constitution.Diterpene-kind compound of the present invention to colon cancer cell (HT 29, HCT 8), hepatoma carcinoma cell (Bcl 7402), nonsmall-cell lung cancer (A549) and/or breast carcinoma (MCF 7) with very strong inhibitory action, wherein positive drug control is better than to the inhibitory action of colon cancer cell (HT 29, HCT 8), hepatoma carcinoma cell (Bcl 7402) and breast carcinoma (MCF 7);On the other hand, compound I will be weaker than positive drug to the inhibitory action of normal cell (Human umbilical vein endothelial cells VEC), show that the compounds of this invention I has antitumor action, and with certain selectivity. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104817432-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104817432-B |
priorityDate | 2015-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.