http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104784685-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-17 |
| filingDate | 2015-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104784685-B |
| titleOfInvention | The preparation method of the hydroxypropyl dimethyl ethyl ammonium chloride chitosan/carboxymethyl chitosan NDV nanoparticles of N 2 |
| abstract | The preparation method of the hydroxypropyl dimethyl ethyl ammonium chloride chitosan/carboxymethyl chitosan NDV nanoparticles of N 2, is related to a kind of preparation method of virus nano grain.It is that chitosan nano to be solved is low to the envelop rate and drugloading rate of vaccine antigen, the mucous membrane surface adsorption capacity difference the problem of.Method：First, the HFCC of N 2 preparation；2nd, the preparation of the hydroxypropyl dimethyl ethyl ammonium chloride chitosan/carboxymethyl chitosan NDV nanoparticles of N 2：A, ewcastle disease L systems virus liquid is added dropwise into the HFCC solution of N 2, stirring, obtains solution A；B, solution A is stirred, N is added dropwise, O carboxymethyl chitosan solutions, obtains solution B；C, solution B is centrifuged, precipitation washing, dries, produce the hydroxypropyl dimethyl ethyl ammonium chloride chitosans of the N 2/N for loading Newcastle disease attenuated live vaccine, O nanometer carboxymethyl chitosan particles.Nanoparticle biological safety prepared by this method is high, good antimicrobial effect, and envelop rate is high.For preparing NDV nanoparticle. |
| priorityDate | 2015-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.