http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104784113-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 2015-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104784113-B |
| titleOfInvention | A kind of composition containing Linezolid and preparation method thereof |
| abstract | The present invention relates to a kind of composition containing Linezolid, it is made up of Linezolid, sodium citrate, citric acid, glucose, water for injection, the pH value of composition is 4.6~5.0, and citric acid is with C 6 H 8 O 7 Its consumption is counted for 1.06mg/ml~1.22mg/ml, sodium citrate is with Na 3 C 6 H 5 O 7 It is the mg/ml of 1.81mg/ml~2.06 to count its consumption, and present invention also offers a kind of preferred preparation method：The water for injection of 60% volume is taken, 55 ± 5 DEG C are heated to, glucose and citric acid is added, after being stirred to dissolve completely, Linezolid is added, after being stirred to dissolve completely, sodium citrate is added, after dissolving completely, plus water for injection（55±5℃）To full dose, 0.02%~0.05% is added（w/v）Activated carbon, stirring and adsorbing 15min, take off charcoal, adjust pH value 4.6~5.0, filtering, it is canned, 121 DEG C sterilizing 12min, packaging.The product unknown impuritie content is lower, and more preferably, security is higher for product stability, and prepares simple and quick, and cost is lower. |
| priorityDate | 2015-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.