http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104761735-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L77-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K5-1515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 |
| filingDate | 2014-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104761735-B |
| titleOfInvention | A kind of preparation method with the cross-linking sodium hyaluronate gel for suppressing hyaluronidase activity |
| abstract | The present invention relates to a kind of preparation method for the cross-linking sodium hyaluronate gel for having and suppressing hyaluronidase activity.This method is utilized under different acid-base conditions, different groups is activated in hyaluronic acid sodium molecule, and then control different acid-base conditions to introduce Hyaluronidase inhibitor in hyaluronic acid sodium molecule, finally give with the cross-linking sodium hyaluronate gel for suppressing hyaluronidase activity.The cross-linking sodium hyaluronate gel that the patent is prepared has the advantages that viscosity is low, the internal residence time is long compared to gel prepared by traditional handicraft, at the same can suppression hyaluronidase activity, highest inhibiting rate is up to 65%.The low viscosity of the standby cross-linking sodium hyaluronate gel of the patent system ensure that the convenience used of clinic, suppress hyaluronic acid enzyme activity and significantly improve the internal residence time, had a good application prospect in terms of injection beauty, artificial vitreous and regression shape arthritis supplementary therapy. |
| priorityDate | 2014-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.