| abstract |
The invention discloses a method for synthesizing 2-substituted benzothiazole derivatives, which comprises using aldehydes and disulfides as raw materials and synthesizing 2-substituted benzothiazoles under the combined action of at least one of NaHCO 3 and AcOH and metal sulfides. Benzothiazole derivatives. The specific reaction is as follows: Among them, R includes one or more of hydrogen, C1-C4 alkyl, fluorine, chlorine, bromine, amino, cyano, nitro, and R' substituents include C1-C6 alkyl, furyl, thienyl , pyrrolyl, pyridyl, at least one of substituted phenyl. The method has stable and easy-to-obtain raw materials, and can synthesize 2-substituted benzothiazole derivatives quickly, conveniently and with high yield. |