http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104745587-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 |
filingDate | 2015-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104745587-B |
titleOfInvention | Nucleic acid aptamer for identifying connective tissue growth factor and its application |
abstract | The invention discloses a group of nucleic acid aptamers for recognizing connective tissue growth factor and its application. The nucleic acid aptamers that specifically recognize the full length of protein CTGF and N-terminal or C-terminal amino acid fragments are successfully screened through the SELEX method. The results show that the nucleic acid aptamers prepared in large quantities by artificial synthesis can specifically recognize and bind the full length and amino acid fragments of the protein CTGF, and have high specificity and sensitivity. Nucleic acid aptamers are comparable to or even superior to antibodies in terms of affinity and specificity, and are expected to be developed as powerful tools for detecting the full-length and N-terminal or C-terminal amino acid fragments of protein CTGF in vivo and in vitro. |
priorityDate | 2015-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.