abstract |
The present invention relates to formula (I) benzoxazepine Compounds, including stereoisomers, geometric isomers, tautomers or pharmaceutically acceptable salts thereof, wherein Z 1 is CR 1 or N; Z 2 is CR 2 or N; Z 3 is CR 3 or N; Z 4 is CR 4 or N; and B is a pyrazolyl ring, imidazolyl ring or triazolyl ring, the compound has anticancer activity and more specifically inhibits PI3 kinase activity. |