http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104744420-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-62
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-02
filingDate 2015-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104744420-B
titleOfInvention The preparation method and application of procyanidin tetramers is extracted in a kind of exosper from sorghum
abstract The invention discloses the preparation method and application that procyanidin tetramers are extracted in a kind of exosper from sorghum, its step:A, SPC mix powders are dissolved in water, after being extracted through ethyl acetate, freeze-drying;B, methyl alcohol is dissolved in, through membrane filtration, loading to Toyopearl HW 40 (s) gel chromatographic columnses;C, with methyl alcohol as mobile phase, using the light absorption value of the ultraviolet-uisible spectrophotometer every pipe eluent of detection, merge the eluent in the corresponding collecting pipe of each elutriated fraction, vacuum concentration, freeze-drying.A kind of application of procyanidin tetramers in treatment or Adeflor M Tablets thing.Adopt and be extracted with ethyl acetate, remove water-solubility impurity and OPC high polymer, improve the purity of OPC oligomer so that gel chromatography is more preferable to separating preparation effect including the oligomer including procyanidin tetramers.By influenceing the structure of glucosyltransferase catalysis activity area albumen in streptococcus mutans and destroying its activity, intervene the generation of carious tooth.
priorityDate 2015-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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