http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104744375-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 |
| filingDate | 2015-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104744375-B |
| titleOfInvention | A kind of guanidine NTR1 small molecular antagonists |
| abstract | A kind of guanidine NTR1 small molecular antagonists.The present invention relates to drug design and field of pharmacology.The present invention is tested by virtual screening and cytoactive and the structural modification based on acceptor is there is provided the compound with general formula I, wherein, R 1 It is hydrophobic group；R 2 It is substituted aroma ring；R 3 Polar substituent group.The compound has inhibitory activity to NTR1, has important use in the medicine of the preparation disease related to NTR1 albumen. |
| priorityDate | 2015-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.