http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104739807-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2015-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104739807-B |
| titleOfInvention | A kind of total toadpoison lactone nano-micelle preparations and preparation method thereof |
| abstract | The invention discloses a kind of total toadpoison lactone nano-micelle and preparation method thereof.Said preparation is made up of total toadpoison lactone of therapeutically effective amount, polyglycol derivatization phospholipid, POLOXAMERS, lyophilized caffolding agent, pH adjusting agent and NaCl.Total toadpoison lactone nano-micelle that the present invention is provided is the supramolecular structure being self-assembly of in aqueous by amphipathic nature block polymer, total toadpoison lactone is encapsulated in hydrophobic inner core, its dissolubility can be improved, and hydrophily shell can avoid the identification and capture of reticuloendothelial system, extend the circulation time in vivo of micellar system, the bioavilability of medicine is improved, is conducive to improving the stability of preparation. |
| priorityDate | 2015-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.