http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104725645-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F230-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F293-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-48 |
| filingDate | 2015-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104725645-B |
| titleOfInvention | It is a kind of to be used to transmit polymer nano vesicle of medicine and liquid fluorocarbon and its preparation method and application altogether |
| abstract | The present invention relates to a kind of acid-sensitive amphiphilic triblock polymer, the polymer is made up of acid-sensitive section of 1 acid-sensitive section of 2 triblock copolymer of polyethylene glycol, described acid-sensitive section 1 is polyacrylamide base phenyl boric acid, described acid-sensitive section 2 is poly- aminoacyl dimethyl-ethylenediamine, the molecular weight of the polyethylene glycol is 2000~5000, described acid-sensitive section 1 of molecular weight is 2000~6000, and described acid-sensitive section 2 of molecular weight is 1000~2000.The invention further relates to above-mentioned acid-sensitive amphiphilic triblock polymer to prepare the application in being used to transmit the polymer nano vesicle of medicine and liquid fluorocarbon altogether, the nano vesicle has uniform nanometer grade diameter, stable circulation and can be enriched in tumor locus in vivo；The nano vesicle of the present invention has good enhancing ultrasonic development ability so as to realize the application of ultrasonic contrast under the conditions of diagnostic ultrasound simultaneously, the polymer nano vesicle also has ultrasonic sensitive, cavitation effect is excited under conditions of the irradiation of low frequency high energy ultrasound, realizes the controlled release of medicine. |
| priorityDate | 2015-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.