http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104725364-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
| filingDate | 2015-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104725364-B |
| titleOfInvention | The amine derivative of 6,7 dimethoxyquinazoline 4, its preparation method and medical usage |
| abstract | 6,7 dimethoxyquinazoline 4 amine derivative of one class containing benzimidazole structure, it is characterized in that it has below formula： R in formula 1 Represent：Hydrogen, methyl, methoxyl group, hydroxyl, chlorine, fluorine, trifluoromethyl；R 2 Represent：Hydrogen, methyl, fluorine, chlorine, bromine, trifluoromethyl；R 3 Represent：Hydrogen, methyl, ethyl, fluorine, chlorine, bromine, trifluoromethyl；R 4 Represent：Hydrogen, fluorine, chlorine；R 5 Represent：Hydrogen, chlorine；Result of study shows, 6 containing benzimidazole structure of the present invention, the amine derivative of 7 dimethoxyquinazoline 4 has significant inhibitory action to mouse melanin tumor cell (F10) and human cervical carcinoma cell (Hela), therefore 6 containing benzimidazole structure of the present invention, the amine derivative of 7 dimethoxyquinazoline 4 can apply to prepare anti-tumor drug.The invention discloses its preparation method. |
| priorityDate | 2015-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 144.