http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104725303-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-82
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-82
filingDate 2015-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104725303-B
titleOfInvention The synthetic method of one kind 2 chlorine N (base of 4 ' chlordiphenyl 2) niacinamide
abstract The invention discloses a kind of synthetic method of 2 chlorine N (base of 4' chlordiphenyls 2) niacinamide.Method is using o-chloronitrobenzene and 4 chlorophenylboronic acids as raw material, through the nitrobiphenyl of Suzuki coupling reactions generation intermediate 4' chlorine 2, after through the aminobphenyl of reduction generation intermediate 4' chlorine 2, target product 2 chlorine N (base of 4' chlordiphenyls 2) niacinamide finally is made with the condensation of 2 chloronicotinoyl chlorides.This method is used for the preparation of 2 chlorine N (base of 4' chlordiphenyls 2) niacinamide, with reaction condition is gentle, technique simple, and cost is low, the advantages of high income.
priorityDate 2015-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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