abstract |
The present invention provides an acetyl-CoA-producing microorganism obtained by adding a microorganism selected from the group consisting of (a), (b), (c), (d) and (e) below to microorganisms not having the following The enzymatic activity of at least one of the group consisting of malate thiokinase, malyl CoA lyase, glyoxylate aldehyde ligase, 2-hydroxy-3-oxopropionate reductase and hydroxypyruvate reductase; (a ) a carbon dioxide stationary cycle with an enzymatic reaction from malonyl CoA to malonate semialdehyde or 3-hydroxypropionic acid, (b) a carbon dioxide stationary cycle with an enzymatic reaction from acetyl CoA and CO to pyruvate, (c) Carbon dioxide stationary cycle with enzymatic reaction from crotonyl CoA and CO2 to ethylmalonyl CoA or glutaryl CoA, (d) with enzymatic reaction from CO2 to formic acid Carbon dioxide fixed cycle, (e) at least one selected from the group consisting of malate thiokinase and malyl CoA lyase. |